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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568

    Email: zhiyuansw@163.com

    info@cydextrin.com

    Address: Boxing Economic Development Zone, Binzhou, Shandong, China

Hydroxypropyl-beta-cyclodextrin

DMF No.: 030168 CAS: 128446-35-5; 94035-02-6; 136019-12-0 Standard : USP39/ EP9.0/ CP2015 Qaulity : Pharmaceutical grade / injection grade / cosmetics grade / industry grade

DMF No.:  030168

Name: hydroxypropyl- beta-cyclodextrin  

Other name : hydroxypropyl betadex ; 2-hydroxypropyl-beta-cyclodextirn ;

Hydroxypropyl-β-cyclodextrin .

Abbreviation : HPBCD

CAS: 128446-35-5; 94035-02-6; 136019-12-0

EINECS: 420-920-1

Molecular formula :C42H70-nO35(C3H8O2)n

Molecular weight: 1134.98+58n

Qaulity : Pharma grade / food grade / cosmetics grade / industry grade 

Standard : USP39/ EP9.0/ CP2015

Package: 500g/bag , 2kg/bag,  10kg/drum , 20kg/drum or customized

 

Specification :

ITEMS

SPECIFICATION(USP39)

RESULTS

Appearance

white powder, insipid, innocent

Qualify

Assay

≥98%

99.5%

 Degree of Substitution

2.8-10.5

5.5

Clarity of solution

50%(w/v) water solution is clear

clear

Identification(IR)

 same absorption bands with USP Hydroxypropyl Betadex RS

Qualify

Loss on Drying

≤10%

4.5%

 

Conductivity

10%(w/v) water solution ≤200µS/cm

 

70

Propylene oxide

≤1ppm

<0.18ppm

Propylene glycol 

≤2.5%

0.05% 

Sum of Other Impurities

≤1%

0.51% 

Betadex

≤1.5%

0.39%

Residue on Ignition

≤0.2%

0.09%

Heavy Metal

≤20ppm

<10ppm

chloride

≤0.05%

<0.05%

Bacterial endotoxins

≤25EU/g

<20EU/g

TAMC(cfu/g)

≤1000

80

TYMC(cfu/g)

≤100

30

Salmonella/E. Coli (cfu/g)

Absent

Absent

Storage: at room temperature, in tightly closed container.

Applications:

Hydroxypropyl-beta-cyclodextrin  is one of the most widely used cyclodextrin derivatives in current scientific researches and industry applications. It mainly used in food, pharmaceutical and cosmetics industries.

 1. In pharmaceuticals industry, hydroxypropyl-beta-cyclodextrin  can increase solubility and bioavailability of insoluble drugs, so that the efficacy of drugs can last longer with less ingestion of drugs. It can adjust and control drugs release ratio, decrease side effects of drugs, and enhance stability of drugs. hydroxypropyl-beta-cyclodextrin  can be used for oral medication, injection, mucosal delivery systems (including the nasal mucosa, rectum, cornea, etc.), dermal drug delivery systems, lipophilic drugs targeting delivery, and also used as protective agent and stabilizer of protein.

    2. In food and perfume industry, hydroxypropyl-beta-cyclodextrin  can enhance the stability of nutritional constituent and extend active time of effective constituent. It can cover up bad smell and bad taste of nutritional constituent. It also can improve production processes and product quality.

    3. In cosmetics industry, hydroxypropyl-beta-cyclodextrin  can reduce stimulate of organic molecular in cosmetic to the skin and mucosa. It can enhance the stability of matter, by preventing oxidation and volatilization of nutrients.




If you're looking for the high-quality hydroxypropyl-beta-cyclodextrin, our company must be your best choice. We're one of the leading manufacturers and supplier with rich experience and wide expertise. Please be rest assured to buy the products from our factory.


 

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Address: Boxing Economic Development Zone, Binzhou, Shandong, China
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 Fax:+86-543-2605568
 E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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