Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-2616568

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

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Application Of Cyclodextrin In Nasal Cavity Administration

Nasal administration is small dose drug systemic absorption of an effective to the form of medicine. But because

 of protein and polypeptide drugs of large particle size, strong hydrophilicity, through the mucosa of the poor and

 after nasal absorption and low bioavailability. Cyclodextrin can by enhancing drug water solubility or promote

 nasal absorption and improve nasal administration of biological utilization degree.

Cyclodextrin in nasal drug delivery system in the safety of the study showed that the cyclodextrin non-toxic, clinical

 laboratory data also confirmed that no side effects.

Cyclodextrin can produce the following effects in nasal cavity liquid preparation:

1 increase the solubility of poorly soluble drugs

2 enhanced drug stability

3 reduce the side effects of drugs on the mucosa

4 to enhance the permeability of the nasal mucosa, while improving the bioavailability of drugs

 

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Address: Boxing Economic Development Zone, Binzhou, Shandong, China
Tel: +86-0543-2616568
 Fax:+86-543-2605568
 E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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