Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-543-8128044

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

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Hydroxypropyl Beta Cyclodextrin In The Field Of Medicine Application

Increase the water solubility of insoluble drugs

HP beta CD can be easily dissolved in water, at room temperature, the solubility is generally greater than 50g / 100mL, and even up to more than 80g / 100ml. When the concentration is less than 40%, good fluidity, viscosity is small. For the pharmaceutical industry can improve the drug solubility without the use of organic solvents, surfactants and lipids. Insoluble drug with its enveloping can significantly increase the water solubility. After the formation of a drug with HP beta CD complexes and its concentration increased with HP beta Cd concentration increased linearly.

Increase the drug stability, improve the bioavailability of drugs

Drugs in the process of storage, can be affected by light, heat, humidity, and many other factors, a direct impact on the quality of drugs. Therefore, the stability is an important index to evaluate the.HP- beta CD on drug inclusion after drugs into the hole, to prevent the volatilization of drugs, sublimation, oxidation and see light decomposition.

HP- beta -CD with a combination of drug dissolution rate of fast, fast release, and can increase the absorption of drugs in the body, is conducive to improve the bioavailability of drugs.

Reducing the toxic and side effects of drugs

It can significantly reduce the toxicity and irritation of the drug to the human body by the way of the combination of the difficult soluble drugs.

Hydroxypropyl beta cyclodextrin can be used as medicine for oral, injection, mucosal drug delivery systems (including nasal mucosa, rectum, cornea and so on), percutaneous absorption to drug delivery system, lipophilic target to the drug carrier, also available protein protective agent and stabilizer.

 

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Address: Boxing Economic Development Zone, Binzhou, Shandong, China
Tel: +86-0543-8128044
 Fax:+86-543-2605568
 E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
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