Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
Categories

    Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd

    Tel: +86-13562317646

    Fax: +86-543-2605568

    Email: info@cydextrin.com

    Add: Boxing Economic Development Zone, Binzhou, Shandong, China

Home > News > Content

Study On The Solubilization Of Hydroxyethyl Beta Cyclodextrin To Rutecarpine

Recently, Navy General Hospital Department of pharmacy researchers published papers, is intended to improve the solubility and bioavailability of rutaecarpine in water, using hydroxypropyl beta cyclodextrin on the for inclusion, broaden the avenues for medicinal rutaecarpine. The study shows that the hydroxypropyl beta cyclodextrin of rutaecarpine has good solubilization, through the package co generation greatly improves the solubility of rutaecarpine and provide the basic research data for the further development of rutaecarpine in use. The paper was published in the 2015 issue of the 04 issue of the Journal of naval medicine.

Using ultrasonic method for the synthesis of Evodia rutaecarpine - hydroxypropyl  beta cyclodextrin inclusion compound and by powder X-ray diffraction analysis, differential scanning calorimetry and infrared spectral analysis and other methods of preparation of rutaecarpine hydroxypropyl beta cyclodextrin inclusion complexes were identified and characterized, using high-performance liquid phase chromatography the solubility of inclusion were determined.

Rutaecarpine alkali and hydroxypropyl beta cyclodextrin inclusion complex was formed, the inclusion of Rutaecarpine is 90.40 times the alkali solubility of mg/L.

 

Contact Us
Address: Boxing Economic Development Zone, Binzhou, Shandong, China
Tel: +86-0543-2616568
 Fax:+86-543-2605568
 E-mail:info@cydextrin.com
Shandong Binzhou Zhiyuan Biotechnology Co.,Ltd
Share: